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After all, to persist in the brain for many years, T. gondii must not do too much damage to its host, continually stimulating the release of anti-inflammatory molecules which limit tissue damage while letting the infection persist.
These appeared in Suns published at Wapping and, even earlier, in Bouverie Street, and are a reminder of the paper's history when it was selling more than 4m copies a day, continually stimulating debate and often setting the political agenda.
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The circulation of knowledge continually stimulates new knowledge.
In special treatment-resistant cases, surgical insertion of electrodes which continually stimulate the greater occipital nerve bilaterally may be considered.
"It's this idea that circuits that are continually stimulated over and over again until they strengthen.
No, I don't plan on becoming a circus performer, but I do know that it is extremely important to continually stimulate my brain with different coordination exercises... to grow my neural network.
Individuals continually stimulate each other, making the process self-reinforcing.
If levels of MMP-9 were continually stimulated to increase, MMP-9 could induce inflammation by activating IL-1β, an auto-inducible cytokine central to the inflammatory reaction [ 33].
For example, prolonged exposure to estrogen, especially during adolescence, is among the strongest risk factors for eventually developing IBC, presumably by allowing genetic alterations to accumulate in ER-positive cells continually stimulated to proliferate [ 11].
Conversely, NK cells can influence the behaviour of accessory cells in return, either by the secretion of cytokines, such as IFN γ, or by cytotoxicity sculpting the subsequent immune response by altering the ability of the APC to continually stimulate inflammatory leukocytes.
The T-cell army will have to be continually reinforced by stimulating the memory T-cells again and again.
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