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The extracellular matrix is continually remodelled by the action of various enzymes such as heparanase, which specifically targets heparan sulfate (HS) and is found in human platelets at high levels.
The endocrine pancreas is continually remodelled [ 1] in a dynamic process involving the death and regeneration of beta cells.
Development of the heart in vertebrate embryos is a complex process in which the organ is continually remodelled as chambers are formed, valves sculpted and connections established to the developing vascular system.
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The brain is continually remodeling itself as you learn from your experiences.
It is continually remodeled by bone cells such as osteoblasts, osteoclasts.
Cytoskeletal structure is continually remodeled to accommodate normal cell growth and to respond to pathophysiological cues.
The cells of our bodies are continually remodelling their architecture by responding to a range of imposed biomechanical forces and intracellular functional demands.
Recently, however, our conceptual view of this isolated organelle has been profoundly altered with the discovery that mitochondria function within an integrated reticulum that is continually remodeled by both fusion and fission events.
Starting there, 400 years of continually remodeling everyday experience has produced a description of reality incompatible with common sense; that reality includes quantum mechanics, general relativity, natural selection and neuroscience.
Previous in vivo experiments with green fluorescent protein-labeled FtsZ and fluorescence recovery after photobleaching have shown that the Escherichia coli Z ring is extremely dynamic, continually remodeling itself with a half time of 30 s, similar to microtubules in the mitotic spindle.
Because mineralized tissue is subject to damage and is metabolically active, mineralized bone is continually remodeled by the action of the basic multicellular unit (BMU) [11].
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