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And their immediate disappearance in the later stages of infection in resistant genotype libraries and continued expression in susceptible genotypes supports a hypothesis that continual expression of this protein may lead to mitochondrial dysfunction and subsequent cell degeneracy.
While HPV expresses several viral proteins in an infected cell, only the continual expression of E6 and E7 are necessary for cellular transformation.
Dinneen JL, Ceresa BP (2004a) Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity.
The larval expression of flippase then promotes the excision of a STOP cassette from another trans-gene allowing a constitutive promotor (Actin5C) to drive continual expression following excision.
Studies have shown that continual expression of these two genes is necessary to maintain malignancy, while suppression of both genes results in cellular death.
The continual expression of BLIMP1 with upstream regulator SOX17 in Wk4 Wk9 hPGCs likely sustains the epigenetic program toward comprehensive 5mC erasure.
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Continual SCL expression during differentiation results in markedly increased hematopoiesis.
A notable observation is that the context CS did not appear to induce continual Arc expression over the entire 30 minutes, but rather appeared to induce Arc during the initial 5 10 minutes of context exploration.
With a connected camera televising our life in-the-moment, accumulated information takes a back seat to continual self-expression.
Continual re-expressions of rage against a deposed tyrant are not necessarily the most productive building blocks for societies torn down by decades of violent kleptocracy.
Likewise, continual intra-cardiac expression of TNF-α promotes the development of cardiac allograft hypertrophy (Stetson et al., 2001).
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