Sentence examples for continual activation from inspiring English sources

CTX irreversibly abolishes the GTPase activity of the Gs α subunit, inducing continual activation of adenylyl cyclase and increased intracellular levels of cAMP.

Once in the brain, these molecules can then stimulate a neural pathway called the hypothalamic-pituitary axis (HPA), the continual activation of which can cause problems over time, says Sarah Wakefield, a child and adolescent psychiatrist at Texas Tech University in Lubbock, Texas says.

Interestingly, the colon had constitutively high levels of NT, which may be attributable to continual activation and surveillance of the gut microbial community by resident macrophages and epithelial cells.

It is conceivable that once TGFβ activates myofibroblast differentiation, the increased deposition of extracellular matrix proteins would cause additional mechanical stress on the cell surface leading to sustained and continual activation of FAK.

Contrarily, chronic inflammation is featured by continual activation of the adaptive immune system that exacerbates the inflammatory response.

However, a sustained heat shock would give rise to ongoing protein denaturation, leading to continual activation of HSPs.

Furthermore, ATP (and thus also ADP) remains sustained for a considerable time near sites of vascular injury (Born & Kratzer, 1984), probably reflecting the continual recruitment and activation of platelets during the haemostatic process.

The greater AUC value with the RCT, which triggers the laryngeal cough reflex [ 5, 21], could be due to the continual and simultaneous activation of cough-associated expiratory muscles with rapid and repeated glottal closure, compared with VC with its brief and often single event of brief glottal closure (Addington et al. cited in [ 22]) [ 1, 3].

Whereas, under cancerous mutation conditions the ERK signal cannot be shutdown and is sustained resulting in the constitutive activation of ERK and continual cell proliferation.

On the other hand, continual excitation may also induce the activation of signal-regulated kinases, such as ERK, p38, and JNK in glial cells.

The lack of dissociation of αqβγ2 (or very brief dissociation) allows continual access to a receptor, a higher level of activation of αq and high level of PLCβ activation and PIP2 breakdown (Fig. 2).