Exact(1)
5 9 14 For sequential and contingent testing, there is no consensus on cut-off levels, resulting in variations in performance measured.
Similar(59)
Introducing NIPT as a contingent test or in first line is expected to reduce the number of procedure-related miscarriages.
More women preferred NIPT as a contingent test than as a primary screening probably because of its high cost.
NIPT is the intervention under consideration and is considered both as a contingent test (ie, as a triage or second line test) and for primary screening (ie, as a first line test).
Whereas NIPT as a contingent test at a price of €460 will lead to short-term savings of about €1.6 million, NIPT in first line has a high impact on budgets, unless the price of NIPT is considerably reduced.
We chose the 90% detection rate as it is that used in the literature for test performances and cutoffs specified for all the screening tests (integrated, sequential and contingent screening tests) used in the first and second trimesters.
Their entry, as the school and class to which they are assigned, is contingent on testing performance.
However, the problems that we had in fitting the data with a standard model were contingent upon testing large elongations, which were not part of that study.
In an RCT of incentives contingent on testing for sexually transmitted diseases in Tanzania, there was a positive effect of the incentive on self-reported behavior change (Packel, Dow, de Walque, Isdahl, & Majura, 2012), and a positive effect of incentives on self-reported motivation (de Walque, Dow, Medlin, & Nathan, 2012).
NIPT will be offered in an NHS setting as a contingent screening test.
For these reasons, in this study NIPT will be included in the current DSS care pathway as a contingent screening test.
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