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Although there is not much genetic variation between the populations of each continent, write Dr. Joanna L. Mountain and Dr. Neil Risch of Stanford University, new data "coincide closely with groups defined by self-identified race or continental ancestry".
Many biologists have replaced the term "race" with "continental ancestry".
More recently, researchers have pursued this hypothesis with genetic-based estimates of continental ancestry.
The analysis of nucleotide and structural variability on human populations has shown that genetic clusters closely correspond with human groups defined by ethnicity or continental ancestry [27] [29].
These studies of continental ancestry in the Americas conclude that individual admixture, and often group ancestry, varies extensively between geographically distinct groups united by the same ancestral label.
Taken together, these results demonstrated that the CoAIMs panel is suitable for determining continental ancestry and admixture proportions for non-admixed and admixed individuals.
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"There are clear differences between people of different continental ancestries," said Marcus W. Feldman, a professor of biological sciences at Stanford University.
We first considered how maternal and paternal continental ancestries that reflect gender-specific admixture patterns at the group level are correlated with the average individual ancestry represented by AIMs for each African-derived American population.
The clustering patterns observed for the five major continental ancestries studied here are similar to those obtained in other studies using larger sets of markers [24], [27], [52], [53].
In contrast, the 93 SNP panel consisted of AIMs selected to identify the continental ancestries of subject groups for genetic studies and demonstrated to be efficient for that purpose.
We genotyped 103 continental ancestry-informative markers (AIMs) for Mexican Americans identified by Kosoy et al. (5), using the Sequenom iPLEX assay (Sequenom, Cambridge, MA).
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