Sentence examples for contiguous probe from inspiring English sources

Copy number aberration calls were made with a minimum regional absolute average log base 2 ratio of 0.25 and minimum contiguous probe count of 5.

Regions of copy number gain and loss were then statistically detected using the Hidden Markov Model (HMM) based segmentation method of the software package with default parameters and the requirement of at least 50 contiguous probe sets.

The parameters for defining CNVs were as follows: significance threshold = 1.0E-6; maximum contiguous probe spacing (Kbp) = 1000 Kb; minimum number of contiguous probes per CNV segment = 5; threshold of signal intensity ratio > 0.2 on the log2 scale for gains and < -0.2 on the log2 scale for losses.

When starting with intact total RNA samples there is no need for contiguous probe coverage of the target, rather a probe spacing of 20 nt less than the minimum anticipated library insert size, or closer, will suffice to obtain even and continuous depletion.

The parameters for defining CNAs were as follows: significance threshold = 5.0E-4; maximum contiguous probe spacing (Kbp) = 1000; minimum number of contiguous probes per CNA segment = 5; threshold of signal intensity ratio >0.2 on log2 scale for gains and < −0.3 on log2 scale for losses.

In five tumors, deletions appeared to be homozygous because signals from contiguous probes were reduced by >50% (Figure 1C, cases 60 and 22); residual signal in these cases likely reflects stromal contamination.

BF measures the confidence we have in the CNV and depends upon signals arising from a number of contiguous probes.

Peaks are extended as long as the log ratio of contiguous probes is greater than the extension threshold.

This expression is most often segmental or involving short series of contiguous probes along the length of longer repeat sequences.

This indicates the equivalent detection sensitivities of the contiguous probes, because transcripts of ISPre1 were detected equally on both strands using different probes shifted by several nucleotides.

The analysis consists of a pre-processing stage which includes image artefact reduction and an algorithm that filters out contiguous probes with unexpected intensity level, if they occur.