Sentence examples for context of the mouse from inspiring English sources

For this reason, we decided to utilize a mouse cell line for our studies and to prepare mutations in ank in the context of the mouse cDNA sequence.

The wild-type sequence of murine ank was used for both transient and stable cDNA constructs of ank, and all mutations in ank were prepared in the context of the mouse cDNA sequence.

In the context of the mouse mammary gland, transcriptome analyses of epithelial cells have highlighted the differences between basal and luminal cells and revealed a number of potential regulators [ 5, 15].

Because differences in recombination rate between the rat and mouse were not taken into account during the analysis, a likely result is the skewing of the genetic map created in the context of the mouse.

The third model used a gene-targeting or KI (knock-in) approach to insert a chimaeric mouse/human exon 1 containing 140 CAG repeats into the murine huntingtin homologue (Hdh) and thus expresses the mutant HD gene in the normal context of the mouse genome (Menalled et al., 2003).

For the preparation of stable transfections via retroviral transduction, ank cDNA wild-type and mutant constructs, prepared in the context of the mouse cDNA sequence, were subcloned into the pLNCX expression vector (Clontech, Palo Alto, CA, USA) and were packaged as directed by the manufacturer.

The multiple alignment in Figure 6 shows a new element on the mouse genome that we found using a profile HMM, in the context of the mouse-human homology.

Recently, in the context of this mouse model, the role of β1-integrin in ErbB2-induced mammary tumor progression was investigated by utilizing the same conditional β1-integrin strain we previously crossed to the PyVmT model of breast cancer [ 55].

Interestingly, in the context of this mouse knockout model absence of CEBPδ resulted in less efficient metastasis under hypoxia, implying that the protein may be required for metastasis at least under these conditions (Balamurugan et al, 2010).

Neither of these gateway nodes has been studied in the context of the aging mouse hippocampus.

In this study, we explored the latter issue in the context of the NOD mouse model for T1DM.