Alternatively, it is possible that 'genuine' effects of drink may be confounded by these learning effects, when present in the context of a crossover design.
The presence of interaction effects on most tasks suggests that subtle changes may occur but are masked, possibly by simple learning effects, in the context of a crossover design.
The RPSFT and IPCW methods used in the analyses of everolimus (Korhonen and Malangone, 2010; Korhonen et al, 2011; Wiederkehr et al, 2011) and pazopanib (Sternberg et al, 2010b) are useful methods for analysing OS in the context of selective crossover (Finkelstein and Schoenfeld, 2011; Morden et al, 2011; Rimawi and Hilsenbeck, 2012).
Specifically, we have considered the phenomenon we observe in the context of the Beam-Film model for crossover interference as suggested (Zhang et al., 2014, PLoS Genetics).
The PISCES study compared patient preference for pazopanib and sunitinib as first-line treatment of mRCC in the context of a randomized crossover trial, and found that 70% of patients preferred treatment with pazopanib because of reductions in fatigue and improved quality of life [ 43].
In this organism, homolog recognition can be genetically separated from synapsis (Colaiacovo et al. 2003); however, DSB repair must take place in the context of the SC to form the obligate crossovers between homologous chromosome pairs (Alpi et al. 2003; Colaiacovo et al. 2003; MacQueen et al. 2002).
The level of precision in crossover is controlled by the sequence context of the two recombining strands of RNA: sequences rich in adenine and uracil decrease crossover precision.
