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We have designed a broad panel of isogenic viruses encoding defined mutants of HIV-1SF2 Nef and analyzed their biological activity in the context of productive HIV-1 infection.
Even in the context of productive infection, pUL135 clearly influenced the HCMV-induced cytopathic effect.
In the context of productive infection, this massive number of proteins confronts the host with plenty of antigens, against which the immune system is simultaneously primed or boosted, thereby raising the likelihood of priming immune cells against a crossreactive epitope and taking the risk of bystander activation.
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The authors demonstrate that long-term, cost-effective resource management can be achieved by managing the contexts of productive systems, rather than by managing the commodities that natural systems produce.
Here we directly determined the role of the vhs protein present in the virus tegument on DC maturation in the context of a productive HSV-1 infection using a recombinant HSV-1 virus deficient in only vhs.
Now is the time to focus newborn health within the broader context of healthy productive lives".
By doing so, it defines productive efficiency in the context of that production set: a point on the frontier indicates efficient use of the available inputs, while a point beneath the curve indicates inefficiency.
Our aim was to explore, in the context of social and productive crises triggered by environmental events, the values and attitudes adopted by smallholders in relation to wild carnivores.
Wage formation at company level in the context of an international productive structure is the subject of Borghijs and Du Caju (1999).
Positive relationships were also mentioned in the context of subspecialties, with productive research networks across sites enabling researchers to benefit from a collective expertise, as well as facilitating study-specific elements such as the conduct of multi-centre trials.
The domestication of farm animals and the development of crops, in the context of ever more productive farming systems, enabled the human population to grow and towns and villages to develop, having governments, laws, trade and economies with specialized employment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com