Sentence examples for context of longevity from inspiring English sources

Invertebrate model organisms, such as yeast, worms, or flies, have been extensively studied in the context of longevity reporting fundamental clues about the mechanisms through epigenetic factors that contribute to aging.

However, in flies, Sir2 lies downstream of the histone deacetylase Rpd3 in lifespan extension [ 13], suggesting that, at least in this organism, chromatin represents the relevant Sir2 target in the context of longevity.

In the context of longevity, NGS has been applied to assess whether ageing is accompanied by an accelerated accumulation of somatic DNA mutations that affects the primary structure of proteins, ultimately compromising organismal functions [ 38].

Both reports show that OGT null mutants decrease longevity in both wild type and daf-2 long living backgrounds, indicating that O-GlcNAc negatively regulates insulin-like signaling in the context of longevity.

Importantly, in the context of longevity, Garagnani et al. (2013) argued that centenarians could be used as ' super controls' to assess the biological significance of genetic markers for age-related diseases, for Type 2 diabetes and the TCF7L2 genotypes.

Although consensus was not achieved, it was possible for those present to acknowledge that specific federal guidelines restrict hGH use to only a few indications, while also recognizing that it is possible to comply with the Code of Federal Regulations (CFR) covering hGH use within the context of longevity medicine.

Increased attention should focus on recognizing and addressing this entirely preventable cancer among HIV-infected women, especially in the context of increasing longevity due to antiretroviral therapy.

The finding that the NMR has a slower nucleotide substitution rate is interesting, particularly in the context of their longevity, and suggests that GM in NMR is superior to GM in the mouse.

These findings indicate that prohibitin is a context-dependent modulator of longevity.

The mitochondrial prohibitin complex, composed of two proteins, PHB-1 and PHB-2, is a context-dependent modulator of longevity.

In this way, immune aging may be described by a dynamic view of the states and interactions of every individual cell and molecule of the immune system and their role in the context of aging and longevity.