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If c :: [e]i and x :: e (c is a context of length i and x is an entity) then c^x is the context of length i+1 that has elements c[0], …, c[i−1], x.
If c is a context of length n, then we refer to its elements as c[0], …, c[n−1], and to its length as |c|.
Here P is a variable of type {0, …, i} → [e]i+1 → [e]j → t, while c is a variable of type [e]i representing the input context of length i, and c′ is a variable of type [e]j representing the output context.
Note that the type {0, …, i} → [e]i+1 → [e]j → t for P indicates that P first takes an index in the range {0, …, i}, next a context fitting this range (a context of length i+1), next a context of a yet unknown length, and then gives a truth value.
Finally, the carboxyl-terminal transactivation domain, a highly variable domain in context of length and sequence among STAT family members, regulates transcriptional activation of target genes through interaction with other transcriptional regulators.
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We will refer to the type of contexts of length i as [e]i.
We have examined the domain contexts of length-deviant domain superfamilies to examine the 'social nature' of such domains and their ability to associate with diverse domain neighbors.
Because both of these epitopes are poorly immunogenic in the context of full length envelope proteins, immunization with properly folded and glycosylated fragments (scaffolds) represents a potential way to enhance the immune response to these specific epitopes.
Thus, this mutation further confirms that also in the context of full length FilGAP and FLNa, the major FilGAP binding site is at the CD face of IgFLNa23.
Mutation of SIM1 in the context of full length Pc2 had little effect on Pc2 sumoylation, but completely abolished it in the context of the delocalized Pc2 2-531) (Figure 5A and B, compare lanes 2, 4 in each panel).
In this report we show that alanine substitution of S303, in the context of full length HSF1, also results in increased levels of trimerized HSF1 both in un-stressed yeast and in mammalian cells.
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