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Only eight modifications showed consistent biases across all three cell types and, even then, only showed these biases in the context of expression (i.e., either for expressed and/or non-expressed genes).
Feedback regulation therefore represents a natural starting point for elucidating the relationship between regulatory principles and the 17 possible sign motifs in the context of expression phenotypes.
It is currently unclear why such variability is observed in flies; however CTG tract sizes, expression levels and context of expression may all contribute to the differences in the observed phenotypes.
25, 10822 10830] suggesting that this activity might depend on the cellular context of expression of the various KChIPs.
This mirrors the context of expression in human tumor types where both squamous and glandular differentiation occur, including cervical and lung carcinomas.
Chemokine biology is thought to have both positive and negative effects on tumor growth depending on the biologic context of expression.
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In the context of ZEB expression, ZEB1 expression is not detected in the normal endometrial epithelium [ 19].
In the context of gene-expression analysis, gene expression profiles often exhibit bi-or multimodality, even when restricted to one phenotype class [ 5].
In the context of gene expression analysis, the primary data is the gene expression data from the microarray experiments.
In the context of gene expression, a low support is critical since high expression coherency is only observed for small groups of genes and conditions.
Therefore we investigated the validity of combining expression patterns of these samples in the context of gene expression differences versus wild type normal mesothelial cells (WTn).
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