Sentence examples for context alteration from inspiring English sources

In contrast, in a disease context alteration in the microbiota with dominance of pathobionts and/or the reduction of beneficial microbes can contribute to disease pathogenesis.

This indicates that, at least in a whole genome context, alteration of either CP or dinucleotide frequencies had no significant effect on viral polyprotein translation and therefore cannot be attributed to the marked differences in replication phenotypes observed.

In this context, alterations of blood transcriptional profiles are a reflection of the immunological response mounted by the host against pathogens.

In this context, alterations of circulating lymphocyte and dendritic cell subsets have been observed, such as plasma cells [ 9], transitional B cells [ 10], pre-switched memory B cells [ 11, 12], regulatory T cells [ 13], CD4−CD8− T cells [ 14] or plasmacytoid dendritic cells (PDC) [ 15].

In the human context, alterations of SRF function due to SRF cleavage by caspase 3 and/or aberrant splicing of SRF transcripts have been described in cardiomyocytes from severely failing hearts, accounting for altered expression of various cardiac-specific proteins that are associated with HF (Davis et al., 2002; Chang et al., 2003; Wong et al., 2012).

In these contexts, alterations in the epigenetic landscape of tissues are likely to occur in order to allow normally restricted cell fate transitions.

To define, in a more physiopathological context, the alteration in the functional performance of mdx/IL6 dystrophic muscle, we forced mice to run on a treadmill, which is also used to accelerate muscle weakness to more closely mirror the muscle pathology seen in patients with DMD (47– 51).

This is the first report that characterized context-specific alteration of c-Fos mRNA expression in the accessory lobe of crayfish during drug-induced reward.

This could indicate context dependent alterations in NG2 cell behavior or fate.

In this context, the alterations of the circulating B-lymphocytes have never been described in detail.

In this context, progressive alterations of the repressive system should sensitize the transcriptional threshold, while keeping on with directionality.