Sentence examples for content of the alignment from inspiring English sources

These results were then filtered by information content of the alignment in the same way as the SWISS-PROT mutagenesis analysis to result in a list of ∼22,000 SNPs.

Note that in the last cycle of search, the algorithm adds/subtracts each segment from query sequences based on its impact to the informational content of the alignment [ 15].

Beyond that conclusion, however, the results were quite uncertain due to the low information content of the alignment, between-branch differences in the evolutionary rates, and uneven sampling of different groups.

However, the crustacean/insect clade on the whole is not well resolved, as by necessity, this phylogeny only included 125 amino acids of the RD as two of the D. pulex sequences are incorrectly annotated and are missing 10 amino acids of the RD, thus reducing the informational content of the alignment.

As alluded to above, the equilibrium GC content of the alignments from which the intronic 64×4 matrices were estimated is often much higher than the equilibrium GC that the matrices generate.

The S parameter (range: 0.7 1.5) is a measure of the information content density of the alignment.

These mutations were all analyzed by B-SIFT and filtered by information content of the SIFT alignment (see Methods), resulting in 12076 remaining mutations of which 408 (3.4%) are called activating and 9736 (80.6%) are deleterious.

In this study we used for the neighborhood scores a window size l w = 21 (w = 10), which we selected on the basis of an autocorrelation analysis of the information content of the domain alignments.

Additional file 4: Figure S4 shows an evaluation, with the program TREE-PUZZLE [ 38], of the internal branch support of the three possible topologies that can be generated with these four groups using likelihood mapping for visualizing the phylogenetic content of the multiple sequence alignment.

The examination of content validity considered the alignment of course objectives with the examination blueprint and the multiple questions.

Infocon identifies blocks of high information content (BHIC) in parts of the alignment and optionally calculates a consensus sequence in each block.