Using examples identified through this search, the article will review information on substandard medicines, including the following: inappropriate API content, impurities and inconsistent pharmacological response due to variable drug content; the prevalence of and potential adverse health effects associated with use of substandard drugs; and methods by which drug quality might be improved.
Also the assessment of total ethanol content and impurity D (HEPES) in the final dose 68Ga-DOTA-NOC appeared not applicable after a risk evaluation.
The effects of metal content, feed impurity, and steaming treatment on the catalytic performances of Pt/mordenite zeolites prepared by different metal incorporation methods were also examined.
The content of impurity depended on the amino acid structure and reaction conditions.
The US Food and Drug Administration and other regulatory agencies set strict limits on the content of impurity C (<1.5 percent).
To ensure compliance with European regulations regarding drug quality, a sample of piperaquine tablets was tested for drug content and impurities, drug concentration was within 5% of the nominal level and analysis of impurities indicated although some impurities exceeded the ICH limit for known impurities [17], all these impurities were identified and none were of concern in terms of safety.
After purification, the content of impurities in NRs was found to be less than 3% in number density (Figure 1b).
Liquid-phase methods are inadequate for obtaining of electrode materials because of the high content of impurities in powders [5,6].
Size (mm) Apparent specific gravity Bulk density (kg/m3) Fineness modulus Moisture content Organic impurities 0.08 8 2.64 1648 3.09 < 0.5 Nil Table 6 Properties of ground calcium carbonate.
The proposed model will estimate the optimal conditions of the five lumps, naphtha, kerosene, light gasoil, heavy gasoil and lowest residue with low content of impurities.
Indian coals of drift origin (Gondwana Coal) can be characterized by high ash content with impurities disseminated in the coal bed.
