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The maximum gene content divergence among strains was approximately 23%, with the majority of strains diverging by 5%to15%5%to15%
The divergence of genomic GC content within disparate Gram negative and Gram positive bacterial phyla indicate that GC content divergence was not produced by a single event that resulted in individual phyla or classes filling a certain GC content niche.
In this study, we demonstrate a correlation between gene expression change and nCpG content divergence between distant species.
Our analysis shows a clear relationship between gene expression change and nCpG content divergence in two distantly related species, such as human versus mouse.
Both lines were then maintained with 20 sires at each generation, without any decrease in the abdominal fat content divergence, which remained close to a factor of three at generation 35.
Under certain conditions, these patterns and biases can change rapidly relative to changes in commonly used marker genes; for example, strains of the marine picocyanobacterium Prochlorococcus marinus show remarkable G + C content divergence from 30%and50%0% despite the presence of very similar 16S rDNA sequences, which is likely due to differences in DNA repair genes (Rocap et al. 2003).
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In addition, we also conducted regression analysis between groups with greater GC-content divergence and calculated slope and R, which were defined as GC-2 pair, GC-3 pair... GC-N pair.
GC-N pair consists of two datasets with larger GC-content divergence and N is the discrepancy between the number of any two datasets (e.g., GC-2 pairs contain the pairs of datasets 1 and 3, 2 and 4, 3 and 5…48 and 50; GC-3 pairs contain the pairs of datasets 1 and 4, 2 and 5, 3 and 6 … 47 and 50).
As a consequence, the covariation of recombination rate, GC content and divergence together with a strong impact of recombination rate on diversity could blur independent signals between divergence and diversity as suggested by the PLSR analysis.
The other two relations are distribution, where the two modes jointly construct similar content, and divergence, where the ideational content is opposed in the two.
The timely-ordered model could describe the consistent decrease of length, GC content and divergence observed in this study.
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