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Studies highlighting the events involved in GH receptor signaling have allowed the development of a pegylated GH receptor antagonist (pegvisomant) for use in humans, which has been designed to outcompete GH for the GH receptor, but which contains a position 120 amino acid substitution that prevents recruitment of a second GH receptor.
The vector of features submitted to the classifier contains a position for each of the groups in the latter scheme.
The more telomeric signal in our 2p region (p25.1 to p24.1) contains a position with relation to families with a higher number of cases and at a younger age at diagnosis [ 11].
This position contains a position 9 polymorphism and so where in other alleles tryptophan or phenylalanine is present, HLA-B*5701 has a tyrosine which is believed to alter the repertoire of peptides that can be expressed and so accounts for the HLA specificity (Chessman et al. 2008).
No consensus HRE (A/GCGTG) could be detected upstream of miR-625-5p miR-625-5p miR-625-5pted during hypoxia), whichas miR-216a-5p contains a 'ACGTGC'(position -42 to -37) and miR-185-3p contains a 'CCGTG'(position -305 to -301).
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The variables message_check and message_translation contain a position in an array of function pointers that can be used to validate the content of a message, respectively translate the content.
Other alignment-free approaches define the local context of sequence positions in terms of overlapping words containing a position (Didier, 1999).
Tabix [ 27] is a generic indexing program for TAB-delimited text files that contain a position column and a value column, and uses the same indexing algorithm as BAM.
First of all, despite the fact that a decreasing number of genes contained a positioned nucleosome as the distance to TSS increased, the proportion of positioned nucleosomes carrying the H3K4me3 mark was constantly high.
The DNA template containing a positioned nucleosome was then remodeled, by either SWI/SNF or ISW1a, for a short period of time (∼1 min), with or without the addition of Gal4DBD.
Given a particle position and the cell containing that position, the algorithm determines the cell which contains a nearby position.
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