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The rate of hydrogen production and of growth by wild-type strain W3110, and four strains containing specific chromosomal gene disruptions were examined (Figures 2A and 2B).
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We cannot exclude the possibility that to a larger extent, several long-range HGLBs were further fragmented by synteny blocks by large evolutionary events, and it is conceivable that chromosomal regions might contain specific "anchor points", which have combined features of long-range chromatin modeling with cis-regulatory and/or other functions.
In particular, labile regions of DNA, known as chromosomal fragile sites, are heritable and contain specific loci that are especially prone to breakage and rearrangement.
Meiotic chromosomes are organized into a series of loops that are tethered to a linear axis containing meiosis-specific chromosomal proteins.
Our study has also flagged hundreds of easily locatable BAC clones from two reptiles and a basal bird that are predicted to contain specific regions of the chicken genome and which can now be mined for specific genes and verified as to chromosomal location via molecular methods.
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Cell-free circulating tumor DNA (ctDNA) contains tumor-specific chromosomal rearrangements that may be interrogated in blood plasma.
The subsequent screening process used for selection of clones containing B. anthracis-specific chromosomal DNA is outlined in Table 1.
This cluster, without any specific chromosomal aneusomy, contains in fact two subgroups.
They intensely pursued a specific chromosomal region that contained several genes that were also present in the candidate list obtained from the Drosophila screen.
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