Sentence examples for containing procollagen from inspiring English sources

Fractions containing procollagen were pooled together.

Surprisingly however, ERGIC-53-containing membranes were displaced from the patches of ER that contained procollagen VII, suggesting that TANGO1 recruits ERGIC membranes to procollagen-enriched ER domains.

In addition, both cell lystaes and cell culture media may contain procollagen aggregates, in which the triple helix may have higher Tm.

This suggests 100 200 TANGO1-cTAGE5 dimers at each exit site and if each TANGO1 (cTAGE5 does not contain a procollagen binding site in the lumen of the ER) binds a procollagen trimer, this would pack 100 200 fully folded trimers of procollagen into a mega-carrier at each ER exit site.

N-TSP2-Fc contained the procollagen homology domain as well as three type I repeats of TSP-2.

The case for support for collagen self-polymerization is strengthened by the fact that collagen is synthesized as a soluble precursor, procollagen, containing N-terminal and C-terminal propeptides.

Type II collagen, the major fibrillar collagen of cartilage, is synthesized as precursor forms (procollagens) containing N- and C-terminal propeptides.

(B ) Building a Procollagen VII containing mega carrier by fusion of recycling ERGIC membranes.

DOI: http://dx.doi.org/10.7554/eLife.10982.010 10.7554/eLiFigure82.011 Figure 6 figure supplement 2. A model for the generation of procollagen VII containing mega-carriers.

(B) HeLa cells lacking TANGO1 (ΔTANGO1) were transfected with a FLAG-epitope-tagged collagen VII plasmid for 28 hr and then incubated for 20 hr with fresh medium containing ascorbate to promote procollagen VII export from the ER.

This resulted in apparent expression of only the IIA mRNA isoform, as confirmed in vitro by splicing of a type II procollagen mini-gene containing the 5′ splice site mutation.