Sentence examples for containing cargo from inspiring English sources

In our case, Slx9 binds RanGTP and the NES containing cargo, and this complex is able to recruit Crm1 directly.

It remains to be tested in a defined system how intact transport complexes, containing cargo, multiple motors, and potential regulatory proteins, react to obstacles on their tracks.

They have been observed containing cargo (suggested to be mRNA [ Paspalas et al. 2009]), and sea urchin vaults appear to contain many proteins (Stewart et al. 2005).

Since the molecular mechanisms by which these latter recognition events occur are distinct from those by which conventional short, linear motif (YxxΦ, ExxxLL, FxNPxY) containing cargo are recognized (Bonifacino and Traub, 2003), the two systems are noncompetitive and so can act in parallel to ensure that both SNAREs and cargo are incorporated into transport vesicles.

We do not quite agree with the reviewers that the concept we are promoting is a variation to RanBP3/Yrb2 for the following reasons: A) Yrb2 binds RanGTP and Crm1 in a cooperative manner and then the complex is presented to the NES containing cargo.

Our use of the term "cooperativity" is based on previous studies, which have shown that the binding of RanGTP and the NES containing cargo to Crm1 is cooperative i.e. the affinity for each binding partner is increased in the presence of the other.

The French also destroyed three large warehouses containing cargoes of spices, rice and opium and captured three ships, losing two men killed when a cannon shot from the shore struck Sémillante.

After this fission process, early endosomes containing cargos destined for degradation undergo intraluminal acidification [by proton-pumping vacuolar-ATPase (V-ATPase)], move along microtubules, and are localized to the perinuclear region before being degraded [12], [13].

Most of importin- β family members, interact with nuclear localization signal (NLS) and nuclear export signal (NES) directly and translocate the containing cargoes.

EhRab7B is localised to late endosomes/lysosome and is involved in the formation and/or fusion to lysosomes, whereas EhRab7A is associated with the post-Golgi compartment containing cargos destined for lysosomes, and involved in fusion to late endosomes.

COPI coatomer-coated vesicles contain cargo indicative of both forward and retrograde transport.