Using CDN, a user can pose clinical queries pertaining to cancer containing aggregations and joins across data hosted by multiple data providers.
The electron picture of syncytial knots appeared nearly normal containing aggregations of small, condensed hyperchromatic nuclei, minimal vacuoles could be seen in the cytoplasm of syncytial knots.
Tri-ortho-cresyl phosphate (TOCP) can cause toxic neuropathy known as organophosphate-induced delayed neuropathy (OPIDN), which is pathologically characterized by the swollen axon containing aggregations of neurofilaments, microtubules, and multivesicular vesicles.
Taken together, these considerations raise the following fundamental questions: (1) how do cells minimize the likelihood of spontaneous aggregation of proteins containing aggregation-prone regions?
After WM treatment, some BFA-induced PIN1-GFP containing aggregations were formed (Fig. 2e and m), but they were morphologically distinct from aggregations induced by BFA alone (Fig. 2b and m).
Notably, all four of the statin compounds in the library caused a unique, reversible neurotoxic morphological effect characterized by intraneurite nodules containing aggregations of organelles ['beads-on-a-string' (BOS)].
However, so far we know very little about the regulation of many proteins that are known to form β sheet aggregates in a cell or proteins that contain aggregation prone segments that are conserved for functional reasons.
Smaug 1 and other proteins involved in mRNA regulation in neurons contain aggregation domains distinct from their RNA binding motifs, and we speculate that self-aggregation helps silencing and transport.
The hypothalamic paraventricular nucleus (PVN) contains aggregations of GLP-1 fibers and expresses GLP-1 receptors, making it a likely site of action for GLP-1 signaling.
The 0.42-Na-H-Bir sample contains aggregations of platy crystals with large size and multiple stacked layers (Figure 2a, b).
Using a transgenic GFP-tagged mitochondrial protein (Pilling et al., 2006), we found that the beads contained aggregations of mitochondria (Fig. 7P S).
