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The fundamental idea is to estimate the DODF based upon the information contained in alignment tensors up to order k, and then use the estimated DODF to evaluate, from Eq. (2), the missing alignment tensor ρ k+1).
The fundamental idea is to use the Maximum Information Entropy Principle (MIEP) in order to estimate the DODF based upon the information contained in alignment tensors up to order k, and then use the estimated DODF to evaluate, from Eq. (2), the missing alignment tensor ρ k+1).
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Through this study, it was found that additional information contained in alignments well below accepted statistical thresholds is also useable to identify domain boundaries and secondary structural elements.
Thanks to the large amount of signal contained in genome-wide sequence alignments, phylogenomic analyses are converging towards highly supported trees.
In the first step, T is restricted to the species contained in the alignment, and for each alignment column i, a relative substitution rate is estimated by numerically optimizing the likelihood of the tree:.
Pairs of orthologs or paralogs were aligned using the BLASTp algorithm and only the protein sequences from regions contained in this alignment were considered homologous and used for global alignment with muscle v 3.8.31 (Edgar 2004).
The phylogenetic information contained in the alignment was visualised using likelihood mapping in TreePuzzle v4.0 ([ 37], ).
2) Mean of the energy z-scores of the individual sequences contained in the alignment (meanz ).
Computing SBMs based on D observed makes most use of the gap information contained in the alignment.
In an elegant approach Korbinian Strimmer and Arndt von Haeseler [ 24] utilized Bayesian posterior probabilities to assess the phylogenetic information contained in an alignment of four homologous sequences.
Hence we can interpret q as a reliability measure for the phylogenetic information contained in the alignment site (relative to C).
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