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In nature, antisense RNAs contain sequences that are the complement of the normal coding sequences found in mRNAs (also called sense RNAs).
Companies will need to show that the additional DNA doesn't contain sequences that can hurt animals or humans, either on its own or by recombining with other DNA.
An analysis of the consensus family motifs using the PATCH program in the Transfac database indicated that 19 of the 30 consensus motifs contain sequences that correspond to experimentally confirmed binding sites for specific plant TFs (Table 1).
The PATCH program of the Transfac database suite indicated that 21 of the 30 identified consensus motifs conform to known plant cis-elements and 19 of these contain sequences that correspond to binding sites for known plant TFs (Table 1) some of which have been shown to regulate the expression of LEA genes (Table 1 and Supplementary File 2).
Both promoter regions of these genes have been predicted to contain sequences that are poorly bound by nucleosomes [11].
In Helicobacter pylori, flanking regions of the IS605 transposase gene contain sequences that fold into identical small stem loops.
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Recent publications of individuals' entire genomes have revealed that they contain sequence that is not found anywhere in the reference human genome [ 14, 15, 25].
Kaminski's groundbreaking work with Spielberg contains sequences that will clearly outlive them both -- the opening D-Day segment in "Saving Private Ryan," a hulking dinosaur staring into a child's window in "The Lost World," the decadent sheen of "Schindler's List".
We also speculate that this region contains sequences that regulate Olig2 expression.
Similarly, NG2(r) contains sequences that carry out some set S2 of enzymatic functions.
The neighborhood of G1, NG1(r) contains sequences that carry out some set S1 of enzymatic functions.
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