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The phrase "contain a large" is not a complete sentence and is not grammatically correct.
It may be used within a larger sentence, but it would need to be followed by a noun or noun phrase to make sense. For example, "The box contained a large amount of cookies" or "Her bag contained a large number of books." In these cases, "contain a large" serves as a verb phrase describing the action of holding or having a substantial amount of something.
Exact(60)
"It could also contain a large amount of methane gas".
As generalities they do contain a large measure of truth.
The C4 isomers contain a large fraction of butadiene.
The genomes of Naegleria and all sequenced Amoebozoa contain a large number of SHKPs.
The seeds contain a large embryo and little or no endosperm.
Beware that these drinks often contain a large number of calories.
Both of these areas contain a large number of unique plant species.
Leachate dams store very toxic liquids, leachate, that contain a large amount of pollutant substances.
They contain a large, double stranded DNA genome of 120 190 kbp.
The latter contain a large amount of In2O3, which leads to poor electrical properties.
They contain a large number of hydroxy groups.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com