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In contrast, for 3 with the counter-anion of octahedral PF−6, pairs of [Ag(py)2]2+2 are organized into a 3-D network via a combined set of Ag⋯F contacts, C(H ⋯F hydrogen bonds, and 'head to tail' π π stacking interactions.
The scores of these induced contacts c i c j (as given by the STRIKE matrix) are then summed up and normalized by the total number of contacts |C| within the template.
We rank the list of predicted contacts and determine the fraction of physical contacts (C β distance ≤ 8 Å) when selecting increasing numbers of contacts.
By 72 hr post-plating, RPE cells lose their pigmentation and begin to form cell cell contacts (C ). 2 weeks post-plating, a confluent monolayer of RPE cells are present that have taken on the typical cuboidal RPE morphology and regained pigmentation (D ).
The gel-forming interactions comprise an essential hydrophobic component (Frey et al, 2006) as well as hydrophilic contacts (C Ader, S Frey, W Mass, D Görlich and M Baldus, in preparation), indirect contacts mediated by NTRs (this study) and possibly also entanglement between different FG repeat domains.
All PPV values were calculated using reference contacts C β (C α in case of glycine) distances in the structure (native or model) with a cutoff at 8 Å. Accurate stereochemistry becomes important when the predicted models are of correct overall fold.
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The only exception is Lys84, which contacts c-di-GMP phosphate groups.
Arrows indicate P. aeruginosa cells contacting (C ) or not contacting (NC) B. thai.
Does adding education to contact (C+E) produce significantly greater change than that produced by contact (C) alone?
Therefore, several questions require investigation: Does contact (C) produce substantive changes, whose nature and magnitude are pre-established?
Does education (E), when added to contact (C), produce substantive changes, whose nature and magnitude are pre-established?
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