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The statistics confirmed unambiguously that the extent of the chondrogenic differentiation increased with cell cell contact, and even a linear relation between differentiation extent and contact extent was established within the examined range.
The selection of the final model for the docked complex was based on factors such as the area of surface contact, extent of interactions, and difference in the binding free energies for complex conformations.
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The cell cell contact effect worked under both hypoxia (5% O2) and normoxia (21% O2) conditions, and the hypoxia condition promoted the chondrogenic induction of MSCs on adhesive microdomains more efficiently than the normoxia condition under the same cell cell contact extents.
For those stem cells in contact, the extent of differentiation was fairly linearly related to the extent of contact characterized by coordination number.
How might Lam6 function to regulate contact site extent?
In the presence of vascular contact, the extent of circumferential contact with the vessel (≤180° or >180°) should be noted as this has been shown to correlate with resectability.
Coalescence occurs when two clusters come in contact, and the extent of coalescence depends on the buffer layer thickness.
We also show that if there is a small initial gap or interference throughout the potential contact area, the extent of the contact area and the stress and displacement fields will approach those of the corresponding receding contact problem as the applied load is increased.
To a certain extent contact rates at EPHC services reflected the reason for immigration.
Human infections are typically through consumption of raw milk or unpasteurized cheese contaminated by the bacterial agent, and to a less extent, contact with infected animals [ 3- 5].
Although it is not clear to what extent contact inhibition occurs in vitro, LaRue et al. [ 14] observed that only the outer two or three cell layers proliferate at the same rate as exponentially growing cells.
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