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Material properties like loss factor and density also alter the contact development.
In order to explicate patient's expectations, the patient-clinician contact was described by a stage model that differentiates between three stages of contact development, and three stages of substantial treatment.
Significantly enriched results (FDR p ≤ 0.05) by cellular and molecular process networks include "development, neurogenesis, axonal guidance", "cell adhesion, synaptic contact", "development, regulation of angiogenesis", "cell adhesion, attractive and repulsive receptors", and "development, neurogenesis, synaptogenesis".
According to her mother, L.'s psychomotor and social development were in the normal range until 2 years of age; she did not notice any difference compared to the early infancy of her son, aged 10: good early interactions, appropriate eye contact, development of appropriate imitation, babbling, shared attention skills and use of functional objects.
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These include a loss of epithelial-like polygonal morphology, basal cell polarity and adhesive contacts, development of a fibroblast-like shape, reorganisation of cytoskeleton filaments, increased cell motility and induction of proteases for ECM degradation requisite for migration and invasion.
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