However, exogenously forced cell cell contact separation leads to the detachment of the adhesion complex from the actomyosin cytoskeleton between β- and α-catenin, suggesting that the weakest link is upstream of α-catenin [33].
The successive process of contact and detachment of aqueous liquid from the solid surface with its resultant net electrical charge generation is termed as "discrete liquid-solid contact electrification", which is unobtrusively ubiquitous in our daily life.
Here we report five effects of cilengitide under such conditions: i) affinity maturation of αVβ3 and its accumulation to the cell periphery; ii) phosphorylation of Src (Y419), FAK (Y397 and Y576/577) and VE-cadherin (Y658 and Y731); iii) disappearance of VE-cadherin from cell-cell contacts; iv) detachment of HUVEC cultured on low-density β1 substrates; v) increased HUVEC monolayer permeability.
This study also identified the receptors through which Sema3C acts and how this leads to breakdown of endothelial cell contacts, cell detachment, and cell death.
Particle approach, contact, adsorption, and detachment as well as adsorption time were studied.
Particle properties governed the approach, contact, adsorption, and detachment steps, and oil viscosity had a significant impact on the contact force and adsorption time.
On August 27 he sent a boat with a few men to make contact with a detachment of Lieutenant Colonel Alexander Dickson's men at Manchac.
In these devices, the abluminal side of the strut and its contact with or detachment from the vessel wall can be directly evaluated by OCT; therefore, the strut thickness is not required for the analysis of apposition.
However, after 24 h incubation with WF (5, 10, 15, 20 and 25 μg.mL-1), morphological changes such as a loss of cell-to-cell contact and subsequent detachment, cell retraction and an altered cell shape were observed.
Overexpression of PDCD6IP restores contact inhibition, promotes detachment-induced apoptosis, and reduces tumorigenicity in nude mice [ 26, 27].
