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Another limitation is the use of a single-dose of each compound in the imaging study, a choice dictated by the complex and time consuming preparation and monitoring procedures used to ensure a tight control of animal physiology during the phMRI experiments.
In addition, the labor intensive and time consuming preparation and analysis of the tissue precludes real time feedback to the clinician.
Direct labeling of peptides modified with the corresponding chelator systems with Ga avoids the time consuming preparation of prosthetic groups usually needed for labeling peptides with F. First approaches to introduce Ga-labeled RGD peptides are focused on the use of DOTA-conjugated RGD peptides.
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The method consisting of drop casting of AQ solution on a CNT modified GCE, in contrast to the time consuming conventional preparation methods with several synthetic steps.
Many of the techniques currently used to analyse collagen fibre architecture require time consuming tissue preparation procedures and are destructive in nature.
Drawbacks of derivatization, namely incomplete reaction and time consuming sample preparation, have been avoided and the change from SIM to MRM mode resulted in increased sensitivity and lower LOQ.
Its advantages over PCR-based techniques are even shorter reaction time, no need for specific equipment, high sensitivity and specificity as well as comparably low susceptibility to inhibitors present in sample materials which enables detection of the pathogens in sample materials even without time consuming sample preparation.
Previous studies have used time consuming sample preparation methods (offline solid phase extraction/derivatization) or methods with rather high detection limits (direct injection) for sucralose analysis.
This conclusion was based on the results regarding the bowel cleansing conditions at 2 hours after consuming the preparation.
Unfortunately, due to work and time consuming sample preparation, the measurement of cellulose molecular weight distributions has a limited applicability until now.
A trial, and the costly and time-consuming preparation needed to wage it, could be problematic for both sides.
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