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Since the generation or acquisition of traditional knockout mice can be difficult and is time consuming, investigators commonly maintain these lines for long periods of time and at significant expense.
Because performance of an OGTT in routine clinical practice is complicated and time consuming, investigators have developed prediction models based on measurements made during the fasting state to predict the risk of future type 2 diabetes (3– 8).
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Since first method is rather time consuming, many investigators adopt the second method as a quick procedure [40].
If this proves to be excessively time consuming, additional investigators will be recruited and trained.
Cohort studies have drawbacks: They are expensive and time consuming, and investigators must carefully plan the exposure assessment component (Rothman and Greenland 1998).
In Qiaotou district, in Sichuan Province, "An old lady named Luo Wenxiu was the first to start consuming human flesh," investigators wrote.
But AOL executives have been occupied for weeks by requests for internal documents and e-mail messages, and by time-consuming interviews with investigators looking at other companies, according to people involved in the inquiries.
Collecting evidence across multiple borders is time consuming and challenging, forcing investigators to navigate each country's laws for data privacy and information sharing.
Despite modest levels of available multiplexing, performing custom or exome hybridization capture on a large population of individuals followed by sequencing and data analysis remains a costly and time consuming proposition for most investigators.
The construction of highly saturated maps is often a time-consuming process, especially if investigators are employing different parental material and markers are not easily transferable.
The construction of highly saturated maps is often a time-consuming process, especially if investigators are employing different parental stocks and markers are not easily transferable.
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