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Therefore, our Ii-gene constructs can be used to immunise for defined CD4+ T cell epitope sequences.
These optimized localization controllable protein constructs can be used to correct for diseases due to aberrant localization of proteins.
Cocktails of mAbs and bispecific constructs can be used to simultaneously target multiple viral epitopes and to overcome issues of neutralization escape.
Because many of the widely used two-hybrid systems employ Trp−, Leu−, His−, or ziocin selection in the shuttle vectors, the Ura+-based pDela constructs can be used directly in those systems.
In conclusion, GFP can be used as an effective and sensitive reporter to monitor specific C. neoformans gene expression in vitro, and GFP reporter constructs can be used as an approach to identify a novel gene(s) or to characterize known genes whose expression is regulated during infection.
Given the high conservation of the PDS locus, silencing constructs can be used successfully across species.
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The method described in the present paper requires an investment of time and effort in the construction of the miRNA expression plasmid, but once cloned the construct can be used indefinitely in future for assays against any sequences of interest.
The LAE construct can be used as a vaccine design platform against various pathogenic diseases.
Transfection studies in vitro showed that this construct can be used to efficiently load MHC class II molecules and present epitopes to MHC class II restricted antigen specific T cells.
Micro-perforated panel (MPP) absorbers are simple to construct, can be used in a variety of applications, show good absorption properties and allow relatively accurate prediction and design under linear conditions.
The fact that our 39AA fusion construct can be re-activated by Mg-ADP (Fig. S1B) suggests this construct can be used for structural study on the Mg-ADP activation mechanism.
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