They also constructed an artifact, which was also made from leaves and branches, but painted silver and encased in a glass cylinder.
While unliganded NEMO(44 111) is characterized by structural instability, upon binding IKKβ it undergoes a conformational change and locks into a stable structure, but it remains unclear whether the conformational heterogeneity of the short construct is an artifact of construct truncation or an intrinsic characteristic of this portion of NEMO required for IKKβ binding.
Because the difference in fold induction between constructs may be an artifact of the high IFN concentration used and the long exposure time, full-length constructs were transfected into HepG2 liver cells, which have been used in previous studies of OAS expression, and treated for 6 h or 24 h [29].
However, Rodebaugh et al. argued that this factor structure might not be a reflection of two distinct, underlying constructs but rather an artifact of the wording of the questions.
In order to identify how end users contribute to product development, we researched the interactions between end users, champions, and professional developers in this online community as they jointly constructed a shared artifact (a web application).
To rule out a construct artifact, the 35S2∶MIR168b construct was rebuilt into a different binary vector and introduced into wildtype Arabidopsis.
The 5′ ends of SINEU elements do not always correspond to the 5′ end of a U1 or U2 snRNA sequence; however, this might be an artifact from constructing consensus sequences from divergent copies.
These findings were both independently supported by experiments performed on three different DNA constructs (please see Table 2 for reference), strongly suggesting that these results are not an artifact of the DNA construct.
Similar results were obtained with transfection of the plasmid constructs, confirming that these results were not an artifact of the viral infections (not shown).
The heroes of modern architecture from Le Corbusier and Mies van der Rohe to Louis Kahn understood architecture to be an extrusion of the earth rather than a constructed artifact to be dropped onto the ground plane.
Instrumental genesis, a psychological construct that describes the process of how an artifact becomes an instrument, illuminates the ways technological tools support mathematics learning.
