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The first step of DetMod algorithm involves the construction of modules starting from a 'seed' protein.
We have devised a method, Semantic Similarity-Integrated approach for Modularization (SSIM) that integrates various gene-gene pairwise similarity values, including information obtained from gene expression, protein-protein interactions and GO annotations, in the construction of modules using affinity propagation clustering.
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Previously, the construction of module maps for cancer patients has revealed important modules that characterize different cancer lineages [ 41], allowing the identification of cancer biomarkers.
A multi-phase experiment was designed to identify 12 representative construction modules; observe the construction of these modules and conduct interviews to determine hazards present; obtain the design documents for the modules observed; and assess the ability of 17 designers to identify the hazards using only design documents.
Our study is part of an on-going project of design and construction of artificial modules for shikimate pathway using synthetic biological tools, aiming to create modules for shikimate pathway that would stimulate industrial applications for bioproduction of aromatic-related primary and secondary compounds.
In other words, the construction of CPD modules should not be a simple reworking or updating of the modules identified for basic training, but should reflect the actual skill deficits reported by the sample.
One important end product of GCENA is the construction of gene modules comprised of highly interconnected genes, and a number of studies have demonstrated that co-expression network modules are generally enriched for known biological pathways, for genes that are linked to common genetic loci, and for genes associated with disease [24] [32].
A generalized design-functional construction of loading modules is developed.
British industry has completed construction of the modules that make up the Lisa Pathfinder satellite.
The construction of two modules used for demonstration of the concept is described.
Unsymmetrical laminates are designed for the use in new lightweight construction of photovoltaic modules.
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