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If this need is met, cloning of the two DNA sequences encoding the variable domains of the specific mAb allows construction of a single chain Fv intrabody construct fused to specific signal peptides for targeting of specific subcellular compartments.
Another factor complicating the conceptualization of the youth alliance construct in contrast to the adult alliance construct is that the youth alliance is not a mutual construction of a single relationship between a patient and therapist.
The needs, he added, "can be met entirely by the construction of a single large facility in a secure environment".
In these, buildings are generally small and scattered, the construction of a single large building being too expensive.
Pan SJ, Rajniak J, Cheung WL, Link AJ: Construction of a Single Polypeptide that Matures and Exports the Lasso Peptide Microcin J25.
We present the design and construction of a single sided magnet array generating a homogeneous field in a remote volume.
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Construction of a single-chain interleukin-12-expressing retroviral vector and its application in cytokine gene therapy against experimental coccidioidomycosis.
In February, a second group based at the University of New South Wales published an article in the journal Nature Nanotechnology reporting their advance: the construction of a single-atom transistor using a different but related design approach.
(A) Construction of a single-gene deletion mutant using the λ Red system.
Next, the construction of a single-span bridge started in the same location.
In addition to the G4S linkers and poly-Gly linkers, many other flexible linkers, such as KESGSVSSEQLAQFRSLD and EGKSSGSGSESKST for the construction of a single-chain variable fragment (scFv), have been designed by searching libraries of 3D peptide structures derived from protein data banks for crosslinking peptides with proper VH and VL molecular dimensions [327].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com