This is because BRCA2 is included in only one original signature and was discarded when we constructed the context-constrained PIN.
They are 'policy advisory systems', which help to construct the context of decision-making (Halligan, 1995; Craft and Howlett, 2012, 2013).
Bit Length Quadtree was presented to replace the Amplitude Quadtree in the improved algorithm, which was used to complete the coding process and construct the context, so the memory usage was greatly reduced during the coding.
However, EZBC used Amplitude Quadtree Q k [l](i, j) and two link lists (LIN and LSP) to finish the coding process and utilized the significance of the neighbor nodes and the node in parent subband to construct the context, so a large amount of memory was required to store Amplitude Quadtree Q k [l](i, j) and two link lists.
In constructing the context-adapted chronic care model (CACCM), they considered the different elements of existing chronic care models (8, 9), methods of implementation and potential results, and the feasibility of implementing these elements to the context.
In consideration of the lower reliability of gene signatures, only the genes that are included in two or more different signatures are used to construct the context-constrained PIN of breast cancer.
After integrating HPRD Human Protein Reference Databasee, http://www.hprd.org/) with a manually curated human signaling network acquired from Cui et al. [ 13], the over-expressed microarray data originated from human adrenal carcinoma cells treated with torcetrapib were mapped to construct the context-specific network.
