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This study was a cohort observational study of prospectively collected data based on the database that was constructed for outcome assurance from January 2004 to July 2008 at Chi Mei Medical Center.
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Six Cox proportional hazards models were constructed for outcomes measured at repeated intervals (≥5 sexual partners; unprotected sex with casual client, regular client, or boyfriend or husband; HIV and pregnancy, all assessed at 3, 6, 9 and 12 months).
An ROC curve was constructed for each outcome.
Separate models were constructed for each outcome variable.
First, an intercept-only model (also called null model) was constructed for each outcome variable.
Separate multivariable logistic regression models were constructed for each outcome variable and each exposure variable, which included relevant confounding variables.
To assess the potential for publication bias, funnel plots were constructed for each outcome in which the log RRs were plotted against their SEs.
Models were constructed for each outcome: number of annual GP visits, number of annual specialist visits, and number of annual hospital bed-days.
Satisfaction with education was ascertained only among participants who recalled receiving education, and therefore only one multivariable model was constructed for this outcome.
Receiver operating characteristic (ROC) curves were constructed for the outcome (death), based on the levels of Ang2, the Ang2/Ang1 ratios on Day 1.
Using baseline values and data from weeks 6, 12, and 20, random coefficient models with random participant effects and random slopes were constructed for each outcome of interest.
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