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We used the same marker genes to construct population reference signals and applied PSEA on each candidate gene.
If expression of siRNA is not uniform in the population or if only a subset of cells expresses the knockdown construct, population methods of evaluating knockdown will introduce ambiguity into the results.
Previous research has suggested that it is relatively easy to construct population databases useful for re-identification about certain sub-populations in Canada because of the information available about them in public and semi-public registries [ 129, 130].
The exposure indicators integrate atmospheric concentration data to construct population exposure indicators at a fine resolution (10 x 15 km grid) based on the modeling of trace metals (nickel-Ni, cadmium-Cd, and lead-Pb) transportation within the Picardy region [ 24].
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The influences may be drawn from historical, cultural, political, scientific spheres or any other source, which can be leveraged to construct populations, which are seen to be more compliant and supportive of biobanking in general.
Moreover, a genotype panel combining exome chips and SNP chip data can help construct population-specific haplotypes carrying rare variants, thus also increasing the imputation accuracy of rare variants.
Even more troubling, how do we handle factually true statements that utilize such a carefully constructed population sample that their argument is almost meaningless?
In this interview excerpt we can see how the constructed population is different depending on who is constructing it, biobankers or policymakers.
In the following, we will briefly discuss the issue of constructed population and the normative problems it has in relation to the legitimation of biobanking activities.
PHYLIP ver. 3.6 [ 57] was used for calculating the genetic distances and constructing population phylogenetic trees.
This form of biobanking represents new ways of constructing populations as engaged and networked.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com