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For the first time, kinetic information from the literature was collected and used to construct integrative dynamical mathematical models of sphingolipid metabolism.
We were able to construct integrative genetic networks from a subset of genes with altered expression due to mating or aging to visualize part of the genetic architectures that underlie these physiological changes.
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The constructed integrative plasmids could not autonomously replicate in methylotrophic cells.
The constructed integrative vectors include a BioBrick-compatible multiple cloning site insulated by transcription terminators, constituting robust cloning interfaces for synthetic biology approaches.
There are many ways to attempt to construct such integrative accounts.
Herein, we attempted to construct an integrative model driven by noise that explores the patterns of temporal cell-fate attainment in the experimental plant, Arabidopsis thaliana (L).
All these data are primary materials required to construct the integrative network for further analysis.
For this purpose, we constructed an integrative expression vector (pEPG-FLO5; Figure 1B) containing the FLO5 gene from S. cerevisiae under the control of EPG1, a promoter not repressed by glucose and induced by anoxic conditions.
In the current study, to further define molecular characteristics of acquired antiestrogen resistance we constructed an "integrative network".
With the above data, we constructed an integrative network based on which an optimization model can be built to detect oncogenic modules and pathways.
Furthermore, Hackenberg et al. constructed an integrative tool of miRanalyzer, which can identify and quantify both known and novel mature miRNAs [ 26].
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