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Neither p53 nor NF-κB/RELA upregulated expression of the reporter construct based on this promoter (miPPPR21-luciferase; Additional file 4), indicating that p53/NF-κB regulated mir-21 expression through GIS but not miPPPR21.

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The versatility of this antibody construct, based on the presence or absence of an Fc domain mutation, provides for improved pharmacokinetics in both imaging and therapy making it a very attractive fragment for continued study and development.

A 3 t/d-scale gasification system was constructed based on this concept.

The compounds were then sorted in decreasing order by their KLS value, and a ROC plot was constructed based on this ordering.

An implicit unstructured DBE method is constructed based on this strategy and is evaluated using several test cases of flow over a backward-facing step, lid-driven cavity flow, and flow past a circular cylinder.

Considering this drawback, the true grade and tonnage of a deposit can be vastly different from the estimated figures and the mine plan constructed based on this resource model tends to fail to achieve production targets and revenue expectation (Baker and Giacomo 1998; Vallee 2000; Dimitrakopoulos et al. 2002; Groeneveld and Topal 2011; Groeneveld et al. 2012).

As an example shown in Fig. 1, the full-length enriched cDNA libraries constructed based on this protocol showed smear of cDNAs with a wide range of molecular weights, suggesting no noticeable bias of DinoSL on types of cDNAs.

To understand the structural basis of Png1p and the role of the N-terminus, a molecular model of Png1p was constructed based on this crystallographic structure [1X3W] (Fig. 2A, C).

A nomogram was constructed based on this logistic regression model.

Once an appropriate model was established, a ML tree was constructed based on this model of sequence evolution.

Furthermore, the phylogenetic trees of nine kinds of protein sequences of H7N9 avian influenza virus were constructed based on this method.

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