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Let us construct a new network by scaling the distances between the nodes of the original network (see Figure 6) by a factor of and the maximum node transmission power by a factor of (note that ).
We construct a new network formed by clusters, where each cluster is turned into a supervertex and there are edges between supervertices if the representative clusters are linked to each other.
The genes with similar functions can be reused to construct a new network.
The cluster with a significant value of 0.001 remained in order to construct a new network containing 295 nodes.
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And then, with the combined BP-SOM idea of Weijters, we construct a new integrated network ICBP KSOM.
Using the learning procedure described in the previous section, for each functional category C, we estimate a parameter matrix W C. In the next step, W C will be used to construct a new association network that is specific for C. Note that, it is more computationally efficient to estimate and store a single functional network for all categories.
We also applied STRING database [ 22] to construct a new DEG PPI network (Supplementary Material 4), which is also characterized as scale-free (Supplementary Material 5).
For validation purpose, we also prepare a new dataset for NSCLC (GSE10245 [ 21]) whose sample size is 58 and repeat the above procedures to construct a new lung cancer-specific functional association network.
We plan to combine these two graphs such that for example the user can select edges in the association network and interactively construct a new complementary SNP graph.
Recently, we explored a different database containing phenotypic knowledge— the semantic network in Unified Medical Language System (UMLS and constructed a new phenotype network called Disease Manifestation Network (DMN) (Chen et al., 2015).
We need to construct a new financial ledger.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com