Dyax recently signed a joint venture agreement with Genzyme to finance half the cost of advanced clinical trials of Dyax's new drug, known as DX-88, used to treat hereditary angioedema, a potentially fatal disorder that can constrict air passages.
Furthermore, all pregnant women were understood to have more difficulty catching their breath than women who were not expecting a child, but in fat women this problem was exacerbated as fat further constricted the breathing passages.
The mutation responsible for the condition ends up stunting the growth of the long bones in the arms and legs, bowing the vertebral column, and often constricting the passage through which the spinal cord runs.
Physiologically, it acts to "expand breathing passages, constrict blood vessels, and increase arterial blood pressure". It is the increase in arterial blood pressure that causes severe hypertension, stroke, or heart attack.
Added to that were high levels of ground-level ozone, nitrogen dioxide, sulfur dioxide and particulate matter, all of which can inflame and constrict the air passages in the lungs and set off asthma attacks even in people who have never had them.
Gautama waited his turn, and as he did he felt that he and the other men had entered some strange enclosed world — there was a world that was spacious and normal, where people drove home at night, and, next to it, off to the side, was another world, a world so constricted that living in it was like walking a narrow passage between two walls.
Briefly, cells were isolated by mild trypsinization (0.05% w/v) and dissociated by repeated passage through a constricted Pasteur pipette in a DNase solution (0.1% w/v).
Anatomical variations of structures creating the osteo-fibrous tunnel for the SN can increase the risk of this pathology by constricting the nerve passage.
All the above suggest that the size of the ACSL relies to some extent on the size of the STSL, however, the STSL is the main factor constricting the SN passage area.
It is also possible that athletes could have allergic reactions to specific pollutants, causing their air passages to become irritated and constricted.
