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The problem is that he hasn't had many constraints of late.
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The primary goal of this study was to assess the effect of normal tissue constraints on late toxicity and quality of life (QOL) in the era of IMRT and image-guided radiation therapy (RT).
Trying to encourage him to be unpredictable, that is, but just a little -- enough to keep things lively, but not enough to overwhelm the narrow stylistic constraints of a late-night talk show, which can be one of the most deeply predictable formulas on the air.
Second, that the lack of a corresponding increase in female reproductive lifespan reflects evolutionary constraint on late-life oocyte production.
In this section we show that the problem of minimizing the number of vehicles used subject to the constraint that the number of late orders is minimum can be solved in polynomial time.
The following algorithm finds a solution with a minimum number of vehicles used under the constraint that the number of late orders is minimum by pushing some orders to an earlier departure time for delivery.
Theorem 2 Algorithm MV finds an optimal solution with the minimum number of vehicles used under the constraint that the number of late orders is minimum in O ( z 2 n 2 log n ) time.
I dare to wonder just what would this Gates do without the burden or constraints of being what the late poet June Jordan so aptly called a "representative other".
These results suggest that selective constraints, not phylogenetic constraints, explain the rarity of late-successional N-fixing trees in temperate forests.
However, constraints on plasticity – both the onset of late ontogenetic canalization and the costs of compensatory development – may be asymmetrical for different developmental trajectories induced by false early information.
With a larger cohort, longer follow-up, and data regarding patient-reported QOL, we hypothesized that patients who met this strict rectal constraint would have both lower rates of late gastrointestinal (GI) toxicity, and improved patient-reported QOL.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com