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What is needed is an algorithm that reconstructs stoichiometrically balanced pathways in increasing order of complexity, with relaxed mass-balance constraints in comparison to the traditional pseudo-steady-state restriction.
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This increased genetic constraint in comparison to the average metabolic pathway may relate to a relative lack of gene duplicates in these pathways.
In two cases, the dN/ dS value before the stop was indicative of strong selective constraints (<0.1), in comparison to the value detected after the stop (>0.9), which suggest that the biological function may have been preserved.
To analyze the evolutionary rate of the new canine predicted gene sequences in a phylogenetic context we used the 232 mouse genes in addition to human genes and dog predicted genes to assess the levels of selective constraint of each lineage in comparison to the rest of the tree.
The high-likelihood miRNA targets predicted in this paper using strict biological constraints produce very different results in comparison to the other Drosophila miRNA target prediction algorithms.
This may be accomplished using either direct or indirect strategies depending on the plasticity of the IAP, economic and social constraints and the phenology of the IAP in comparison to the natives.
Of the algorithms that considered power system constraints, the modified AIMD and DPF algorithms provided the best trade off in terms of achieving almost optimal performance in terms of their grid objectives while satisfying constraints and maintaining a small communication overhead (GOOD) in comparison to the other communication based optimal algorithms considered (UGLY).
Given this constraint, contracts among agents are necessarily finite and incomplete in comparison to the ideal complete contract that we model as infinite in detail.
Nevertheless, because the COSMIC template model is less expressive in comparison to the openEHR archetype model in the areas of data value constraints, spatial structural constraints and terminology related constraints, the possibility of successful round-trip conversion depends on whether the subject of conversion falls in the shared subset of supported constraints from the two formalisms.
It uses the local and global structural properties of the entire NOE network in comparison to the available tridimensional protein structure, to obtain assignment constraints.
The constraint loss or the notch effect produce a relaxation in the triaxial stress field in comparison to the severe stress fields present at deeply sharp cracked specimens.
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