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This type of constraint on change in ratio within a biosynthetic pathway, coupled with differences in ratios between compounds from distinct biosynthetic pathways, might provide enhanced information content.
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Other studies have demonstrated selective constraint on changes in gene expression between mammals [ 11- 13] and in the fly [ 14].
However, it appears that worry is not enough to implement risk reduction measures if there are real or perceived constraints on change.
Because the more densely connected structures have much higher synchronization than other patterns, and fewer constraints on change propagation, environments characterized by these types of STMs may be prone to rapid, complex transitions in response to environmental changes.
The link between micro- and macro-evolutionary changes in the branch and polypar features of P. bipinnata seems to be related to constraints on change in some already-fixed features, but implies integration of changes in branch length with other unconstrained traits: inter-polyp distance, which varies widely among species [ 3], was constant at the intraspecific level.
The melting of the Eemian interferes with gas-based paleothermometry, and with the total-gas technique that provides constraints on changes in surface elevation.
Since WC-1 plays a dual role as both a photoreceptor and as a core clock component, there are specific constraints on changes in its activity.
There were no constraints on changes in the dose of methotrexate, use of other DMARDs including previously untried agents, or on use of oral, parenteral or intra-articular corticosteroids once patients were included in the study.
The model endogenously determines the optimal deployment of technologies subject to a constraint on climate change.
This introduces a constraint on the change in gene expression against mutations.
The fit and fitness of interaction domains places a powerful constraint on evolutionary change within these cellular machines.
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