Generally, DNA CpG hypermethylation is thought to result in decreased expression of the affected genes, whereas hypomethylation could release the spatial constraints on access of the transcriptional machinery to the regulatory sites of the gene; this could thus enhance the chances of transcription of the gene [3] [9].
We believe that many more children may have been killed in incidents that cannot be properly verified because of constraints on access.
Technological advances, particularly in cyberinfrastructure, have quietly chiselled away at all the constraints of access to travel, colleagues, collections, literature, and data that held back Linnaeus and the generations of taxonomists who have followed.
Olomi and Urassa (2008), in the study based in Tanzania, identified three major groups of constraints of access to finance by SMEs.
Other health system factors that relate directly to adolescents' work activities such as appropriate opening hours, reduced HC waiting times, and adapted outreach programs, have to be further evaluated in order to address more structural constraints of access to ANC.
Currently, appeals are based on what is programmatically achievable given constraints of access and partners, rather than what is required to avert disasters.
The issues of infrastructure, cross-community water sales and pricing, and constraints on access to Great Lakes water are complicated here.
Lack of information on price, source and quality of medicines procured, distributed and used in health sectors of LMICs is a constraint to access.
2) Inadequate economic resources or poverty-related factors (e.g., time constraints, lack of access to transportation, unsafe environments) may result in foregoing or postponing medical services.
Dr. Chan and Mr. Lake agreed that the commitment of governments and the implementation of strategies to overcome local constraints to access and use of essential services are critical success factors.
In addition, urban form's effects on community facility distribution patterns under the constraints of pedestrian access to urban road networks remain poorly understood.
