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Threonine in position 158 is also a well-conserved amino acid that forms hydrogen bonds with two conserved residues (P128 and C129) in the loop between the first transmembrane domain and the pore helix, and thus constrains the structure.
This threonine lies in the loop between the selectivity filter and the second transmembrane domain; its hydroxyl group forms hydrogen bonds with conserved residues in the loop between the first transmembrane domain and the pore helix, which constrains the structure.
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From the NMR PDB ensemble of 1G6M it can be inferred there are 4 disulphide bridges that constrain the structure making it more ordered (Supplementary Text S2).
Nevertheless, using methods that seismologists developed to study seismic waves, the scientists modeled the hydromagnetic waves to constrain the structure of the magnetic field in the outer core and the rigidity of the solid inner core.
These are used to constrain the structure and seismic properties of the lithosphere and primarily to measure the thickness and infer the bulk composition of the crust.
Nine conserved disulfide bonds constrain the structure of NPC1L1 NTD), with Domain A containing six and Domain B containing two disulfide bonds.
This in turn suggests that it will not be possible to determine which ecological or evolutionary processes are constraining the structure of mutualistic networks by studying their degree distributions alone.
These results show that in spite of its approximations, i.e.: use of implicit solvent, neutralization of local charges, constraining the structure of the SH2 domain, the simulated annealing approach, as implemented in this work, yields reliable results in identifying the conformational trends of phosphopeptides complexed with SH2 domains.
Observed intermediate points were then used to constrain the structure of these phenotypic landscapes.
This hydrogen bond would probably constrain the structure of the hairpin loop and the β-sheet adjacent to the major MgATPase active site in NBD2.
Though the above is a scenario in which ontologies are used to interpret and classify existing data, ontologies can also be used to guide the creation of structured data, in a manner akin to how an XML schema is used to constrain the structure of a valid XML document.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com