The comparison of consecutive (i.e., with a delay of 20 to 30 min) with the simultaneous TOF-MRA/PET suggests that retrospective spatial alignment is a mandatory step in case that angiography and PET cannot be acquired truly simultaneously, e.g., when dictated by other constrains of the overall study, as in this work.
This offset was dictated by other constrains of the overall study.
Many techniques have yielded insight into alcohol's effects on the organism, but perhaps the most challenging field, given the logical ethical constrains, is the study of the neuronal structures and mechanisms that are affected by alcohol and/or which play a role in the development of AD in living humans.
Based on the explained problem with the consent, a GP constrained the feasibility of the study only on home visits that took place in private homes.
Interpretation is constrained by some limitations of the study.
Specifically, the lack of replication in these aspects of the mitigation process limits the inferential potential of the study, constrains the ability to make accurate predictions about the probability of success of future mitigation endeavors, and impedes our understanding of the critical mechanisms governing successful habitat creation, restoration, and enhancement.
Species level relationships are not constrained as most of the studies include very few species so that they represent poor tests of lower level phylogenetic structure.
Additionally, we obtained luminescence ages of alluvial fan and colluvial deposits, which allow us to better constrain the late Pleistocene sedimentation history of the study area.
As with all NJR-PROMs studies, the design of the study was constrained by the data available.
The generalisability of the study is constrained by the limited number of participating health facilities and the small sample size.
