These constrains made difficult to define the actual impact of the infection; however, since the penetration of active larvae is followed by a considerable antibody response, an alternative to parasitological/biochemical/molecular analyses of the biopsy material could be a non-invasive serology.
Selling portfolio companies onto public markets has been constrained, making it ever harder to return funds to investors.
Families torn apart, markets, schools, hospitals destroyed or rendered inaccessible, and economies constrained, making it harder and harder for ordinary people to work their way out of poverty.
One explanation for this is that as additional contact points between the peptide and protein are added, the peptide becomes increasingly sterically constrained, making it impossible to add further contact points that are structurally independent [17], [20], [42].
You are not constrained to making money within two or at most three years.
"A lot of these smaller data centres may be in a room in an office building where they feel like they are constrained from making modifications," says Kava.
But the initial write-down could mean that banks with limited capital would be constrained from making as many loans as they otherwise would make.
The public trust of the prosecutor's office would suffer if he were constrained in making every decision by the consequences in terms of his own potential liability in a suit for damages.
Ron Bonjean, a Republican strategist and once the top spokesman for the former House speaker J. Dennis Hastert, a Republican, described the phenomenon thusly: "These are people who are political realists, they're political pragmatists who want to see progress made in Washington, but are politically constrained from making compromises because they will be challenged in the primary".
Ron Bonjean, a Republican strategist and once the top spokesman for J. Dennis Hastert, a Republican and former House speaker, described the phenomenon thus: "These are people who are political realists, they're political pragmatists who want to see progress made in Washington, but are politically constrained from making compromises because they will be challenged in the primary".
