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On the other hand, up to now, the maximum dimensions of the bulk amorphous and nanocrystalline alloys that can be directly prepared are still quite limited, typically no more than centimeters, thus constraining their applications in many situations.
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The utilisation of formal mathematical models constrained their application to well-structured problems of a nature that could generally only be found within the larger more bureaucratic organisations.
Nonetheless, the poor chemical and biological stability of DNA and RNA constrain their applications.
Accordingly, the manufacturing cost is relatively high which constrains their wide applications.
Apart from huge drug delivery potential of dendrimers, toxicity associated with their positively charged surfaces, constrains their biomedical applications.
However, the limited capacity, high expense, and high power loss of VSCs currently constrain their commercial application.
Heretofore, there have been a number of comparative studies for feature selection, but they have either considered settings with much smaller dimensionality than those occurring in current bioinformatics applications or constrained their study to a few real data sets.
Previous methods based on cline width analysis are constrained in their application by the geographic localization of cline centers.
The modulation level and the number of allocated time slots for every sensor are constrained to attain their applications bit rates in a global energy-efficient manner.
This shortcoming may constrain the full potential of their applications.
While computer tools are available to assist in sustainability assessment, their applications are constrained to a specific domain of the design synthesis problem.
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